It is known as the “capital of the Peruvian Amazon”. The city is in the Great Plains of the Amazon Basin, fed by the Amazon, Nanay and Itaya rivers. The area was long inhabited by indigenous peoples until the Spanish established the town around 1757 as a Spanish Jesuit reduction by the banks of the Nanay River. In the late 19th century, the city became the center of rubber production and exports from the Amazon Basin and was the headquarters of the Peruvian Amazon Company. The Historic Center of Iquitos features The Cathedral of Iquitos, the Iron House, the Old Hotel Palace, and Cohen House. Other landmarks are the Plaza de Armas; Jiron Prospero, and the lively neighborhood of Belén, often dubbed the “Amazon Venice” for its many waterways.